Engineered Elegance: Generating the Wait Anaphase Signal
anaphase, aneuploidy, cancer, chromatid pairs, chromosomal instability, chromosomes, colon cells, developmental abnormalities, Down syndrome, inhibitory complexes, Intelligent Design, kinetochores, Medicine, metaphase, microtubules, mitotic spindle, phosphatase, prometaphase, safety belt, spindle assembly checkpoint, tumorigenesis, tumors, yeast
Even a single unattached kinetochore is sufficient to trigger the wait anaphase signal, which inhibits activation of the APC/C that drives entry into anaphase. Source