Recalling Francis Collins’s The Language of God

Bill Clinton, Center for Science & Culture, China, COVID-19, Darwinian evolution, David French, ENCODE, Evolution, Faith & Science, Francis Collins, John West, Junk DNA, National Institutes of Health, proteins, Religion News Service, The Language of God, The Origin of Species, theology, vaccinations, Wuhan
President Bill Clinton announced, in a speech Collins helped to write, “we are learning the language in which God created life.” Source
Read More

Why Systems Biologists Now Assume Life Is Optimally Designed

"poor design", bioinformatics, biological structures, biologists, biosphere, Dan Graur, ENCODE, engineers, Eva Balsa-Canto, Evolution, fitness landscape, human body, Human Errors, human genome, Intelligent Design, Julio R. Banga, Junk DNA, knee, Living with Darwin, Nathan Lents, Nikolaos Tsiantis, optimality, pelvis, Philip Kitcher, scientific materialism, teleology, whales, Wikipedia
Purported examples of poor design usually represent opinions resulting from armchair critics’ limited understanding of the technical literature. Source
Read More

Excerpt: Letter to the Journal of Chemical Education

A Mousetrap for Darwin, biochemical pathways, Darwinian theory, Darwinism, DNA, Evolution, Intelligent Design, Journal of Chemical Education, Junk DNA, letter to the editor, molecular machinery, philosophy journals, polymerase, random mutation, science journals, Scientific American, Skeptics, students
Unlike philosophy journals — or high school newspapers — many science journals are unwilling to publish responses by people attacked in their pages. Source
Read More

Paper Shows that “Mutational Load” Arguments Don’t Refute ENCODE

Atheism, Dan Graur, deleterious mutations, ENCODE, Evolution News, fitness, functional, genome, Genome Biology and Evolution, Intelligent Design, Junk DNA, molecular evolution, mutations, predictions, Science (journal), University of Houston
When the ENCODE project first proposed, on the basis of direct empirical research, that 80 percent of the genome may be biochemically functional, a huge prediction of intelligent design was fulfilled. Evolutionary biologists saw the writing on the wall and were quick to fight back. Perhaps one of ENCODE’s staunchest critics has been Dan Graur, a molecular evolutionary biologist at the University of Houston. He argued in 2017 in the journal Genome, Biology and Evolution that ENCODE’s empirically based conclusions could not possibly be correct because “Mutational load considerations lead to the conclusion that the functional fraction within the human genome cannot exceed 15%.” What exactly is “mutational load”? Mutational load is based upon the principal that populations of organisms can only tolerate a certain number of deleterious mutations before they reach a critical level…
Read More

The “Why” of the Fly “Y”: Reflections on “Junk” DNA

Alison Nguyen, axioms, Carmen Sapienza, chromosomes, DNA, Doris Bachtrog, Drosophila melanogaster, Emily Brown, euchromatin, Evolution, Francis Crick, fruit fly, genetics, heterochromatic proteins, heterochromatin, Junk DNA, Leslie Orgel, nucleus, organism, phenotype, repetitive sequences, Richard Dawkins, RNA, The Selfish Gene, transposable elements, W. Ford Doolittle, Y chromosome
In April 1980, almost exactly forty years ago, the journal Nature published a pair of highly influential articles on the topic of what has become known as “junk” or “selfish” DNA. Both reflected the key concept of The Selfish Gene, the highly influential 1976 book by Richard Dawkins, namely, that organisms are merely DNA’s way of making more DNA. The first was authored by W. Ford Doolittle and Carmen Sapienza and titled “Selfish genes, the phenotype paradigm and genome evolution.”1 The second was authored by Leslie Orgel and Francis Crick and titled “Selfish DNA: the ultimate parasite.”2 Together they posited an easy-to-grasp way to conceive of “excess” nucleotides along chromosomes — repetitive sequences in general and transposable elements in particular. In short, it was proposed that most such DNA elements…
Read More

More Hints of Order in the Genome

Abo1, Amir Bitran, ATP, biochemistry, Biozentrum, Caulobacter crescentus, central dogma, Chelsea R. Bulock, chromosomes, cohesin, cotranslational folding, Darwinian mechanism, DNA, E. coli, error catastrophe, genome, GGC, GGU, Intelligent Design, Junk DNA, Lego blocks, misfolding, mRNA, Nature Communications, Patricia Clark, PNAS, polymerase, polypeptides, Polδ, proofreader, proteins, RNA, South Korea, strand breaks, UNIST, University of Basel, University of Notre Dame, University of Seville, William Paley
Genomics has come a long way since the central dogma (the notion that DNA is the master controller that calls all the shots) and junk DNA (the expectation that much of the genome is non-functional). If scientists ditch those old dogmas and approach the genome expecting to find reasons for things, they often do. Synonymous Mutations To-may-to or to-mah-to? The British write flavour; the Americans write flavor, but generally each understands the other without too much difficulty. Genomes, too, have alternate ways of spelling things: GGU and GGC in messenger RNA both spell glycine. No big deal, thought geneticists; these “silent” mutations cause no change in the resulting protein. At the University of Notre Dame, however, biochemists are finding that the differences in spelling are not just background noise; they…
Read More

Care for Appetizers? Electric Proteins, Spidey Sense, and More

anatomy, appetizers, Arizona State University, Barry Scott, Biomimetics, centipedes, cilia, electricity, electron transport, gene repression, genes, genomes, Intelligent Design, Irreducible Complexity, Joubert syndrome, Junk DNA, Massachusetts Eye and Ear Infirmary, Massey University, materials science, metabolism, Michael Behe, miRNA, orb webs, photosynthesis, physiology, Siam News, sliders, spiders, Stuart Lindsey, swimming, Tohoku University, University of North Carolina, University of Otago, X-ray crystallography, Zheng-Yi Chen
Welcome to the second day of the New Year! Like tasty sliders, these short news stories should get the juices flowing for big developments in 2020. Electric Proteins Dr. Stuart Lindsey at Arizona State University is an expert in single-molecule dynamics in biomolecules. Older methods of observing protein structure, such as X-ray crystallography, only gave single snapshots of the highly dynamic world, he says, where proteins rapidly change conformations and interact in complex ways. Electron transport has been well known in the cases of photosynthesis and metabolism. But a few years ago, his team was astonished to find that a run-of-the-mill protein conducted electricity. The protein was acting like a wire! Further observations revealed that all proteins conduct electricity — even the ones that had “weren’t designed to do this”—…
Read More

BioEssays Editor: “‘Junk’ DNA… Full of Information!” Including Genome-Sized “Genomic Code”

adenine, Advanced Science News, Andrew Moore, BioEssays, Biological Information: New Perspectives, cytosine, DNA, ENCODE, Evolution, Francis Crick, function, genome, genomic code, Giorgio Bernardi, guanine, Intelligent Design, isochores, Junk DNA, Leslie Orgel, narrative gloss, overlapping codes, proteins, selective pressure, thymine, viral genomes
How many times have we heard it claimed that the vast majority of the human genome is “junk” and therefore could not have been designed? Even in the face of overwhelming evidence from the ENCODE project and numerous other studies showing that most of our genome has biochemical function, most evolutionists still maintain that our genomes are largely junk. But a few brave scientists, including some rare evolutionists, have been willing to buck that trend.  In a new article at Advanced Science News — “That ‘Junk’ DNA… Is Full of Information!” — Andrew Moore, the Editor-in-Chief of the respected biology journal BioEssays, comments on a new BioEssays paper. The paper finds that our DNA contains overlapping layered “’dual-function’ pieces of information,” including a “genomic code” that spans virtually the entire…
Read More